Polynucleotides

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Polynucleotides are an advanced injectable treatment used in aesthetic medicine to improve skin quality, elasticity, and overall texture through bio-stimulation rather than volume replacement.

At Aesthetics Shop UK, we supply professional polynucleotide products exclusively for aestheticians, cosmetic doctors, clinics, and wholesale customers looking to offer cutting- edge skin rejuvenation treatments with natural results and minimal downtime.

Polynucleotides work at a cellular level to stimulate the skin’s natural repair processes, making them an increasingly popular choice for patients seeking gradual, long-lasting improvements in skin health and appearance.

What Are Polynucleotides?

Polynucleotides are injectable bio-stimulators derived from purified salmon or trout sperm DNA. These fragments of DNA and RNA are highly biocompatible with human DNA and well tolerated, making polynucleotides suitable for sensitive skin and delicate treatment areas.

In aesthetic treatments, polynucleotides are utilised to stimulate collagen and elastin production, enhance skin hydration, and promote cell turnover. At a biological level, polynucleotides consist of nucleotide chains made up of nitrogenous bases, sugars, and phosphate groups. DNA and RNA play a fundamental role in cellular repair, protein synthesis, and tissue regeneration.

When injected into the skin, polynucleotides support wound healing, reduce inflammation, and enhance the skin’s ability to produce collagen and elastin, which are essential proteins for maintaining youthful skin structure.

Polynucleotide Treatments in Aesthetic Medicine

Polynucleotide treatments are used to improve skin texture, elasticity, and tone rather than add volume. This makes them particularly effective for fine lines and wrinkles, dark circles, stretch marks, acne scarring, and areas where traditional fillers or skin boosters may not be suitable.

Polynucleotides can be used on the face, neck, hands, and under-eye area, where skin quality and hydration are often compromised. Polynucleotide under-eye treatments are especially popular because they improve skin quality, hydration, and elasticity without causing puffiness or product migration. 

Unlike hyaluronic acid fillers in the area such as tear trough filler, polynucleotides do not attract excessive water and therefore maintain a natural appearance in the delicate under-eye area.

How Polynucleotide Treatments Work

Polynucleotide injections are a minimally invasive injectable treatment performed using fine needles or cannulas. Polynucleotides stimulate collagen production and elastin production by activating fibroblasts and supporting cellular regeneration.

Their antioxidant properties also help protect the skin from free radical damage while improving skin hydration and elasticity.

Over time, this results in a noticeable reduction in fine lines, an improved overall texture, and enhanced skin quality.

After an initial treatment consultation and review of medical history, a topical numbing cream can be applied to help reduce discomfort. Multiple injections are then placed across the treatment area to ensure even distribution of the product within the skin. 

Painful concerns are common among patients undergoing polynucleotide treatment, but discomfort is typically mild and short-lived. Mild redness, swelling, or minor bruising at the injection site may occur and typically resolve within a few hours to a few days after treatment.

What To Expect From The Treatment Results and Course

Results from polynucleotide treatments develop gradually rather than instantly. Most patients begin to notice improvements in skin texture, hydration, and elasticity within four to six weeks as collagen production increases. 

Optimal results require a series of treatments, with the number of polynucleotide treatments needed depending on the skin concerns and brand of product used. Typically, two to three sessions spaced two to four weeks apart are recommended.

Results generally last between six and nine months, after which maintenance treatments help to sustain skin rejuvenation and collagen stimulation. This staged approach yields natural looking results that gradually improve over time, rather than dramatic, immediate changes.

Polynucleotides vs Skin Boosters and Dermal Fillers

Polynucleotides are often compared to skin boosters and dermal fillers, but serve a distinct role within aesthetic treatments. Skin booster injections focus primarily on skin hydration using hyaluronic acid, while dermal fillers restore volume and structure.

Polynucleotides however, improve skin quality by stimulating the body’s own regenerative processes. Many clinics combine polynucleotide treatments with skin boosters, dermal fillers, and anti-wrinkle injections as part of a comprehensive treatment plan. 

This allows practitioners to address volume loss, wrinkles, and skin quality simultaneously while maintaining balance and achieving natural-looking results.

Safety, Suitability, and Aftercare For Your Clients

Polynucleotide treatments are generally considered safe with an excellent safety profile when performed by trained professionals. Due to their natural origin, allergic reactions and adverse effects are rare. Common side effects are typically mild and include redness, swelling, or tenderness at the treated area.

Polynucleotides are suitable for most skin types and concerns but are not recommended for pregnant or breastfeeding individuals. Post-treatment care includes following aftercare instructions, such as avoiding alcohol, strenuous exercise, and active skin treatments like chemical peels for several days after the procedure.

A cold compress may be used if swelling occurs, and patients can usually return to normal activities within a few hours.

Professional Polynucleotide Products at Aesthetics Shop

At Aesthetics Shop UK, we supply only trusted, professional-grade polynucleotide products for wholesale and clinic use. Our range includes leading brands such as Vitaran polynucleotides, ILLuma PN Booster, ILLuma Luna, and Lumi Pro Eyes, all of which have been carefully selected for their exceptional safety profiles, clinical performance, and consistent results.

These products are designed for use by qualified aesthetic professionals who offer advanced injectable treatments that enhance skin quality, elasticity, and hydration, delivering natural-looking results.

Shop polynucleotides today and provide your patients with scientifically backed skin rejuvenation treatments that work at a cellular level to restore youthful skin over time. Get in touch today more information!